Kidney failure is a serious medical condition that can lead to devastating and potentially life-threatening complications, such as permanent kidney damage and death, and kidney failure side effects have been linked to the use of a popular class of Type 2 diabetes drugs called sodium-glucose cotransporter-2 (SGLT2) inhibitors, which includes the prescription medication Invokana (canagliflozin). If you took Invokana to treat your Type 2 diabetes, and you have since been diagnosed with acute kidney failure, kidney damage or severe kidney impairment, contact an experienced kidney failure lawyer today for legal help. You may have grounds to file a product liability lawsuit against the maker of the diabetes medication, in order to pursue financial compensation for your injuries and medical expenses.
Kidney failure, also known as renal failure, occurs which the kidneys lose the ability to balance fluids and remove waste from the body. There are two types of kidney failure, acute renal failure, which occurs suddenly and without warning, and chronic kidney disease, which occurs following longstanding disease of the kidneys. Because SGLT2 inhibitor diabetes medications like Invokana act on the kidneys to help remove glucose from the body, the prescription drugs are contraindicated for individuals with severe kidney impairment, and may be associated with kidney damage or kidney failure complications in otherwise healthy patients with Type 2 diabetes.
There are a number of possible causes of kidney failure, including impaired blood flow to the kidneys, damage to the kidneys, and urine blockage in the kidneys, but a growing body of research has established a potential connection between kidney failure and side effects of the SGLT2 inhibitor class of diabetes drugs. One of a number of possible side effects of Invokana and other SGLT2 inhibitors is dehydration, and when the body becomes dehydrated, the kidneys are unable to function properly and may begin to fail. When the kidneys are no longer able to perform their proper function, dangerous levels of wastes may begin to accumulate in the body, and the chemical makeup of the blood may become out of balance, resulting in kidney failure. The most common symptoms of kidney failure include:
In patients with acute kidney failure, which develops rapidly over the course of a few hours or days, the condition can be fatal and requires intensive treatment to reverse the effects of the renal failure. Treatment for kidney failure typically requires hospitalization, during which doctors are tasked with identifying and addressing the underlying cause of the renal failure, which may include use of the diabetes drug Invokana. In kidney failure patients who are otherwise healthy, it may be possible to recover normal or nearly normal kidney function. However, in some cases of renal failure related to the SGLT2 inhibitor Invokana, the buildup of potassium in the bloodstream caused by the kidneys’ inability to function properly may lead to severe complications like permanent kidney damage, abnormal heart rhythms and even death.
In May 2015, the U.S. Food and Drug Administration (FDA) issued a drug safety communication, warning consumers and the medical community that “the type 2 diabetes medicines canagliflozin [Invokana], dapagliflozin [Farxiga] and empagliflozin [Jardiance] may lead to ketoacidosis, a serious condition where the body produces high levels of blood acids called ketones that may require hospitalization.” The FDA also noted in the same warning, that “In addition to ketoacidosis, other possible side effects of SGLT2 inhibitors include dehydration, kidney problems [and] low blood sugar when this class of medicines is combined with other prescription medicines used to treat diabetes, increased cholesterol in the blood, and yeast infections.”
Type 2 diabetes accounts for more than 90% of diabetes cases in the United States, and Invokana is fast becoming one of the most widely-used methods for treating the lifelong disease. Unfortunately, according to mounting research, Type 2 diabetes patients who take Invokana or another SGLT2 inhibitor medication may face an increased risk of kidney failure and other serious complications, which may become life-threatening without the proper treatment. If you believe you have been adversely affected by kidney failure side effects of Invokana, consult a reputable product liability lawyer to discuss your legal options. With a knowledgeable Invokana attorney on your side, you can protect your legal rights and seek fair and timely reimbursement for your losses.